TRT clinical practice

TRT + Enclomiphene (Fertility-Preserving)

Testosterone cypionate replacement with enclomiphene citrate added to preserve LH/FSH signalling and maintain testicular function and fertility. Enclomiphene blocks hypothalamic oestrogen receptors, keeping the HPT axis partially active despite exogenous testosterone.

Duration

Steps

2

Total Weeks

Route

IM

Protocols

2

Source

clinical practice

Protocol Timeline

Step Weeks Dose Compound Note
1 0 50 mg Testosterone Cypionate 50-80mg per injection (100-160mg/week total). Inject Mon/Thu or Tue/Fri for E3.5D spacing.
1 0 12.5 mg Enclomiphene 12.5-25mg/day. Alternative to HCG for LH/FSH maintenance.

Rationale

Monitor LH, FSH, testosterone (total + free), E2, and semen analysis every 3–6 months. Enclomiphene 12.5–25mg/day.

Compounds Used

Related Tools

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Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.

Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.