HRT_MASC clinical practice

Transmasculine T + Finasteride (Hair Preservation)

Testosterone cypionate standard transmasculine protocol with finasteride added for androgenic alopecia management. Finasteride inhibits 5-alpha-reductase, reducing DHT. For transmasculine patients experiencing or at high risk of male-pattern hair loss on testosterone.

Duration

Steps

2

Total Weeks

8

Route

SubQ

Protocols

2

Source

clinical practice

Protocol Timeline

Step Weeks Dose Compound Note
1 8 50 mg Testosterone Cypionate 50 mg weekly SubQ or IM. Most common clinical starting dose. Check labs at 6-8 weeks.
2 0 50 mg Testosterone Cypionate Maintenance 50-100 mg weekly. Target trough T: 400-700 ng/dL.

Rationale

Begin finasteride only after hair loss is evident — preventive use is debated. Monitor for sexual side effects including reduced libido. The transmasculine experience with finasteride is less studied than cisgender male data. Some transmasc people prefer to accept hair loss rather than reduce DHT-mediated effects.

Compounds Used

Related Tools

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Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.

Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.