Transmasculine HRT — Nebido (Long-Ester)
Testosterone undecanoate (Nebido) for transmasculine patients — the long-acting injectable option requiring only 4–5 injections per year. NHS prescribes Nebido for male hypogonadism and some gender clinic patients.
Duration
—
Steps
3
Total Weeks
6
Route
IM
Protocols
1
Source
clinical practice
Protocol Timeline
| Step | Weeks | Dose | Compound | Note |
|---|---|---|---|---|
| 1 | 0 | 1000 mg | Testosterone Undecanoate (Injectable) | 1000 mg deep IM. Week 0. |
| 2 | 6 | 1000 mg | Testosterone Undecanoate (Injectable) | 1000 mg deep IM. Week 6 (shortened interval for loading). |
| 3 | 0 | 1000 mg | Testosterone Undecanoate (Injectable) | 1000 mg deep IM every 10-14 weeks. Adjust interval based on trough T levels. |
Rationale
Loading schedule same as TRT: inject at week 0, week 6, then every 10–14 weeks. Trough levels at ~12 weeks can be suboptimal for some transmasc patients — if masculinisation progress is slow, discuss shortening interval with prescriber.
Compounds Used
Related Tools
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