Sermorelin

Geref

Peptide peptide SubQ FDA/EMA Label

Half-life

18 min

Time to Peak

9 min

Steady State

~1 days

Dose Range

200–500 mcg

Frequency

Daily

Overview

FDA-approved synthetic 29-amino acid GHRH analog. Originally approved for diagnosis and treatment of GH deficiency in children. Now widely used off-label by anti-aging and wellness clinics for GH optimization. One of the few peptides with full FDA-approved PK data. Requires reconstitution with BAC water.

Mechanism of Action

Binds GHRH receptors on somatotroph cells of the anterior pituitary, stimulating synthesis and release of growth hormone in a physiological pulsatile pattern.

Dosing Information

Route	Dose Range	Half-life	Tmax	Frequency
Subcutaneous (SubQ)	200–500 mcg	18 min	9 min	Daily, five days per week

Storage & Handling

2-8C — Store lyophilized powder refrigerated. Reconstitute with BAC water. Use reconstituted solution within 4-6 weeks.

Used in Regimens

Sermorelin is not currently part of any catalog regimen.

Data Sources

FDA Label Geref (Sermorelin) FDA Prescribing Information

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