Oxandrolone
Anavar · Oxandrin
Half-life
9 hr
Time to Peak
1 hr
Steady State
~2 days
Dose Range
10–80 mg
Frequency
2x daily
Overview
Oral AAS with one of the most extensive published human PK datasets due to ongoing medical use. FDA-approved for weight regain after surgery/trauma, chronic infection, severe burns, Turner syndrome, and HIV wasting. Widely used non-medically due to mild side effect profile. 17-alpha-alkylated but considered less hepatotoxic than most oral AAS. Significant renal excretion (28% unchanged in urine). Harm reduction: While "mild" by AAS standards, still suppresses endogenous testosterone and negatively impacts lipid profiles (reduces HDL significantly). Monitor liver enzymes and lipid panel. 17-alpha-alkylated — do not combine with other hepatotoxic compounds or excessive alcohol.
Mechanism of Action
DHT derivative. 17-alpha-alkylated for oral bioavailability. Does not aromatize. Moderate anabolic, low androgenic. 28% excreted unchanged by kidneys.
Dosing Information
| Route | Dose Range | Half-life | Tmax | Frequency |
|---|---|---|---|---|
| Oral | 10–80 mg | 9 hr | 1 hr | 2x daily |
Storage & Handling
Room temperature — Oral tablets. Store at 20-25C. Protect from light.
Used in Regimens
2 regimensTest/Anavar Lean Cycle
Testosterone cypionate base with Oxandrolone (Anavar) for a lean mass/strength cycle. Anavar is mild, low-androgenic, and well-tolerated — popular for first compound additions. TUDCA liver support required as Anavar is an oral 17-alpha-alkylated steroid.
Anavar 40–60mg/day weeks 4–12 (8-week oral run).
Women's Anavar Cycle
Oxandrolone (Anavar) cycle for women. The only AAS routinely used by women due to its low androgenic rating. Used for strength, lean muscle, and body recomposition. Virilisation is dose and duration dependent — strict limits required.
Anavar 5–10mg/day. Start at 5mg and assess tolerance before increasing.
Data Sources
- FDA Label Oxandrin (oxandrolone) FDA Prescribing Information
- Peer-reviewed Karim A et al. Oxandrolone disposition and metabolism in man
Related Tools
Track Oxandrolone with Doseline
Reminders, medication level charts, injection site rotation, and protocol tracking — all free, all private.
Join the waitlistDoseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.