Nandrolone Decanoate

Deca · Deca-Durabolin

Anabolic Steroid aas TRT IM FDA/EMA Label

Half-life

8 days

Time to Peak

4 days

Steady State

~40 days

Bioavailability

100%

Dose Range

50–600 mg

Frequency

Weekly

Overview

Long-acting nandrolone ester. FDA-approved for anemia of chronic kidney disease. One of the most widely studied AAS compounds. Approximately 6x more anabolic than testosterone with lower androgenic activity. Suppresses endogenous testosterone very strongly — should always be co-administered with exogenous testosterone. Very long detection time (12-18 months) due to fat-soluble metabolite 19-norandrosterone. Harm reduction: Monitor hematocrit, prolactin, and progesterone. Consider cabergoline or P5P for prolactin management if needed.

Mechanism of Action

19-nortestosterone derivative. Binds androgen receptor with high affinity. Lower 5-alpha reduction to DHN (weaker metabolite) compared to testosterone's conversion to DHT. Progestogenic activity contributes to some side effects.

Dosing Information

Route Dose Range Half-life Tmax Frequency
Intramuscular (IM) 50–600 mg 8 days 4 days Weekly, Every 2 weeks

Storage & Handling

Room temperature — Store at 20-25C. Protect from light. Oil-based solution.

Used in Regimens

1 regimen

Test/Deca Bulk Cycle

Testosterone enanthate + Nandrolone Decanoate (Deca) classic bulk cycle. One of the most popular intermediate AAS stacks. Deca adds significant mass with less androgenic side effects than testosterone alone. Requires HCG on-cycle, an AI if needed, cabergoline for prolactin, and full PCT.

Deca 300–400mg/week, 2x weekly injections. Stop 2 weeks before test.

20wk Harm Reduction aas
Primary

Data Sources

  • Peer-reviewed Minto CF et al. Pharmacokinetics and pharmacodynamics of nandrolone esters in oil vehicle
  • FDA Label Deca-Durabolin (nandrolone decanoate) FDA Prescribing Information

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Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.

Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.