NAC

N-Acetyl Cysteine

Ancillary aas Oral Published Clinical Data

Half-life

5.6 hr

Time to Peak

1 hr

Steady State

~2 days

Bioavailability

Dose Range

600–1800 mg

Frequency

Daily

Overview

Glutathione precursor used as general liver and antioxidant support during oral AAS cycles. Also used in clinical settings for acetaminophen overdose.

Mechanism of Action

Precursor to L-cysteine and reduced glutathione (GSH). Replenishes intracellular glutathione stores, the primary endogenous antioxidant, protecting hepatocytes from oxidative damage.

Dosing Information

Route	Dose Range	Half-life	Tmax	Frequency
Oral	600–1800 mg	5.6 hr	1 hr	Daily, Twice daily

Used in Regimens

NAC is not currently part of any catalog regimen.

Data Sources

Peer-reviewed N-Acetylcysteine pharmacokinetics and bioavailability

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