Melanotan II
MT-2 · MT-II
Half-life
33 min
Time to Peak
15 min
Steady State
~1 days
Dose Range
100–500 mcg
Frequency
Daily
Overview
Synthetic cyclic heptapeptide analog of alpha-melanocyte stimulating hormone (alpha-MSH). Primarily used for skin tanning (melanogenesis) and sexual dysfunction. Activates multiple melanocortin receptors (MC1R for tanning, MC4R for sexual function). Not approved by any regulatory agency. Associated with side effects including nausea, facial flushing, and mole darkening. Requires reconstitution with BAC water.
Mechanism of Action
Non-selective melanocortin receptor agonist. MC1R activation stimulates melanin production (tanning). MC4R activation increases sexual arousal. MC3R activation affects energy homeostasis.
Dosing Information
| Route | Dose Range | Half-life | Tmax | Frequency |
|---|---|---|---|---|
| Subcutaneous (SubQ) | 100–500 mcg | 33 min | 15 min | Daily, Every other day |
Storage & Handling
2-8C — Store lyophilized powder refrigerated. Reconstitute with BAC water. Start with low dose to assess tolerance — nausea is common initially.
Used in Regimens
Melanotan II is not currently part of any catalog regimen.
Data Sources
- Peer-reviewed Melanotan II pharmacokinetics and melanocortin receptor activity
Related Tools
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