LL-37
Cathelicidin · hCAP18
Half-life
4 hr
Time to Peak
1 hr
Steady State
~1 days
Dose Range
50–200 mcg
Frequency
Daily
Overview
The only human cathelicidin antimicrobial peptide (AMP). A 37-amino acid peptide produced by immune cells, epithelial cells, and keratinocytes. Broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. Used in the peptide community for immune support and Lyme disease protocols. Available as subcutaneous injection or topical. Requires reconstitution with BAC water for injectable use.
Mechanism of Action
Directly disrupts microbial membranes. Also modulates immune response by recruiting immune cells, promoting wound healing, and modulating inflammatory cytokine production.
Dosing Information
| Route | Dose Range | Half-life | Tmax | Frequency |
|---|---|---|---|---|
| Subcutaneous (SubQ) | 50–200 mcg | 4 hr | 1 hr | Daily, three times weekly |
| Topical | 0.5–2 mL | 4 hr | 1 hr | Daily, Twice daily |
Storage & Handling
2-8C — Store lyophilized powder refrigerated. Reconstitute with BAC water. Also available as topical formulation.
Used in Regimens
LL-37 is not currently part of any catalog regimen.
Data Sources
- Peer-reviewed LL-37 cathelicidin antimicrobial peptide review
Related Tools
Track LL-37 with Doseline
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