Lixisenatide

Adlyxin · Lyxumia

GLP-1 Receptor Agonist GLP-1 SubQ FDA/EMA Label

Half-life

3 hr

Time to Peak

1.5 hr

Steady State

~1 days

Bioavailability

55%

Dose Range

10–20 mcg

Frequency

Daily

Overview

Once-daily injectable short-acting GLP-1 receptor agonist for type 2 diabetes. Taken within 1 hour before the first meal of the day. Also available as Soliqua combination pen.

Mechanism of Action

GLP-1 receptor agonist based on synthetic exendin-4 analog with modified C-terminus. Short-acting with primarily post-prandial glucose effect.

Dosing Information

Route	Dose Range	Half-life	Tmax	Frequency
Subcutaneous (SubQ)	10–20 mcg	3 hr	1.5 hr	Daily

Storage & Handling

2-8C — Refrigerate before first use. After first use: room temp (up to 30C) for up to 14 days. Do not freeze.

Used in Regimens

Lixisenatide is not currently part of any catalog regimen.

Data Sources

FDA Label Adlyxin FDA Prescribing Information

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