Kisspeptin-10
KP-10 · Metastin 45-54
Half-life
28 min
Time to Peak
15 min
Steady State
~1 days
Dose Range
50–400 mcg
Frequency
Daily
Overview
Truncated 10-amino acid fragment of the endogenous kisspeptin neuropeptide. A potent stimulator of GnRH release, leading to downstream LH and FSH secretion. Used in fertility research and by the TRT/peptide community as a natural approach to stimulating endogenous testosterone production. Requires reconstitution with BAC water.
Mechanism of Action
Activates the kisspeptin receptor (KISS1R/GPR54) on GnRH neurons in the hypothalamus, triggering pulsatile GnRH release which stimulates LH and FSH from the anterior pituitary.
Dosing Information
| Route | Dose Range | Half-life | Tmax | Frequency |
|---|---|---|---|---|
| Subcutaneous (SubQ) | 50–400 mcg | 28 min | 15 min | Daily, Twice daily |
Storage & Handling
2-8C — Store lyophilized powder refrigerated. Reconstitute with BAC water. Very short half-life — timing of administration matters.
Used in Regimens
Kisspeptin-10 is not currently part of any catalog regimen.
Data Sources
Related Tools
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