Epitalon

Epithalon · Epithalone

Peptide peptide SubQ IV Case Studies / Guidelines

Half-life

30 min

Time to Peak

15 min

Steady State

~1 days

Dose Range

5–10 mg

Frequency

Daily

Overview

Synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural pineal gland peptide epithalamin. Researched primarily by Prof. Vladimir Khavinson (St. Petersburg Institute of Bioregulation and Gerontology). Proposed to activate telomerase, potentially extending telomere length and cellular lifespan. Limited Western clinical data. Used in the longevity/anti-aging peptide community. Requires reconstitution with BAC water.

Mechanism of Action

Activates telomerase reverse transcriptase (hTERT) in somatic cells, potentially extending telomere length. Also reported to normalize circadian melatonin production via pineal gland modulation and upregulate antioxidant enzyme expression.

Dosing Information

Route Dose Range Half-life Tmax Frequency
Subcutaneous (SubQ) 5–10 mg 30 min 15 min Daily
Intravenous (IV) 5–10 mg 30 min 6 min Daily

Storage & Handling

2-8C — Store lyophilized powder refrigerated. Reconstitute with BAC water. Use reconstituted solution within 3-4 weeks.

Used in Regimens

1 regimen

Epithalon — Telomerase Activation Cycle

Epithalon (Epitalon) tetrapeptide — the most researched longevity peptide. Stimulates telomerase activity, extends telomere length in vitro, and has demonstrated lifespan extension in animal models. Used in the longevity/biohacker community for anti-ageing. Dr Khavinson's intensive 10-day cycle is the standard protocol.

5–10mg SubQ daily for 10 consecutive days.

2wk peptide
Primary

Related Tools

Medication Level Plotter

See blood level curves for this compound

Dose Calculator

Calculate reconstitution and draw volumes

Split Dose Calculator

Divide your weekly dose into multiple injections

Track Epitalon with Doseline

Reminders, medication level charts, injection site rotation, and protocol tracking — all free, all private.

Join the waitlist

Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.

Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.