Dulaglutide

Trulicity

GLP-1 Receptor Agonist GLP-1 SubQ FDA/EMA Label

Half-life

5 days

Time to Peak

2 days

Steady State

~25 days

Bioavailability

65%

Dose Range

0.75–4.5 mg

Frequency

Weekly

Overview

Once-weekly injectable GLP-1 receptor agonist for type 2 diabetes. Pre-filled single-use pen with hidden needle designed to reduce injection anxiety.

Mechanism of Action

GLP-1 receptor agonist fused to modified IgG4-Fc fragment. The larger molecular size extends the half-life to ~5 days.

Dosing Information

Route	Dose Range	Half-life	Tmax	Frequency
Subcutaneous (SubQ)	0.75–4.5 mg	5 days	2 days	Weekly

Storage & Handling

2-8C — Refrigerate. Can store at room temp (up to 30C) for up to 14 days. Do not freeze.

Used in Regimens

Dulaglutide is not currently part of any catalog regimen.

Data Sources

FDA Label Trulicity FDA Prescribing Information

Related Tools

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Dose Calculator

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Split Dose Calculator

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