DSIP

Delta Sleep-Inducing Peptide

Peptide peptide SubQ Nasal Case Studies / Guidelines

Half-life

15 min

Time to Peak

6 min

Steady State

~1 days

Dose Range

50–300 mcg

Frequency

Daily

Overview

A naturally occurring nonapeptide first isolated from rabbit brain in 1977. Promotes delta wave (deep) sleep without sedation. Used in the peptide community for sleep optimization. Can be administered subcutaneously or intranasally. Short half-life but effects on sleep architecture persist for hours. Requires reconstitution with BAC water for injectable use.

Mechanism of Action

Modulates sleep-wake cycles by promoting delta wave EEG activity. Also has stress-protective, antioxidant, and analgesic properties. Does not cause sedation — enhances natural sleep onset.

Dosing Information

Route Dose Range Half-life Tmax Frequency
Subcutaneous (SubQ) 50–300 mcg 15 min 6 min Daily
Nasal 50–300 mcg 15 min 6 min Daily

Storage & Handling

2-8C — Store lyophilized powder refrigerated. Reconstitute with BAC water. Administer 1-2 hours before desired sleep time.

Used in Regimens

1 regimen

DSIP — Sleep Optimisation Protocol

Delta sleep-inducing peptide (DSIP) bedtime SubQ injection cycle for sleep quality improvement. DSIP modulates delta wave sleep activity. Individual response highly variable — some users report transformative sleep improvement, others minimal effect.

DSIP 100–300mcg SubQ 30–60 min before bed.

3wk peptide
Primary

Data Sources

  • Peer-reviewed DSIP delta sleep-inducing peptide pharmacology

Related Tools

Medication Level Plotter

See blood level curves for this compound

Dose Calculator

Calculate reconstitution and draw volumes

Split Dose Calculator

Divide your weekly dose into multiple injections

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Reminders, medication level charts, injection site rotation, and protocol tracking — all free, all private.

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Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.