CJC-1295 with DAC
CJC-1295 DAC
Half-life
8 days
Time to Peak
24 hr
Steady State
~40 days
Dose Range
1000–2000 mcg
Frequency
Weekly
Overview
CJC-1295 with DAC is a synthetic growth hormone-releasing hormone (GHRH) analog with a Drug Affinity Complex that extends its half-life to about 8 days. Often combined with Ipamorelin for synergistic GH release.
Mechanism of Action
Binds GHRH receptors on the anterior pituitary. The DAC moiety binds serum albumin, preventing rapid clearance and maintaining elevated GH levels for days rather than minutes.
Dosing Information
| Route | Dose Range | Half-life | Tmax | Frequency |
|---|---|---|---|---|
| Subcutaneous (SubQ) | 1000–2000 mcg | 8 days | 24 hr | Weekly, Twice weekly |
Common Side Effects
- · Water retention
- · Tingling/numbness in extremities
- · Increased hunger
- · Fatigue
- · Injection site reactions
- · Vivid dreams
Monitoring Recommendations
IGF-1 levels at baseline and 3 months. Fasting glucose and HbA1c (GH can affect insulin sensitivity). Monitor for signs of excessive GH (joint pain, edema).
Storage & Handling
Refrigerated
Reconstituted: 28-30 days refrigerated
Room Temperature
Lyophilized: stable at room temperature
General
Reconstitute with bacteriostatic water. Refrigerate after reconstitution.
Community Notes
The 'Wolverine Stack' (CJC-1295/Ipamorelin) is one of the most popular peptide combinations. Dose before bed on an empty stomach for best GH pulse. The DAC version allows for 1-2x/week dosing vs the no-DAC (Mod GRF 1-29) which requires daily dosing.
Used in Regimens
CJC-1295 with DAC is not currently part of any catalog regimen.
Data Sources
- Peer-reviewed Pharmacokinetics of CJC-1295 with DAC in healthy adults
Related Tools
Track CJC-1295 with DAC with Doseline
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