Buserelin

Suprefact

GnRH Agonist SubQ Nasal Published Clinical Data

Half-life

1.2 hr

Time to Peak

30 min

Steady State

~1 days

Bioavailability

100%

Dose Range

0.2–0.5 mg

Frequency

three times daily

Overview

GnRH agonist available as subcutaneous injection and intranasal spray. Not available in the US but used in Europe, Canada, and other markets. Available as daily SubQ injection or intranasal spray. Also available as depot formulation in some markets.

Mechanism of Action

Synthetic nonapeptide GnRH agonist. Same mechanism as other GnRH agonists -- continuous administration causes pituitary downregulation.

Dosing Information

Route Dose Range Half-life Tmax Frequency
Subcutaneous (SubQ) 0.2–0.5 mg 1.2 hr 30 min three times daily
Nasal 300–600 mcg 1.2 hr 30 min three times daily

Used in Regimens

Buserelin is not currently part of any catalog regimen.

Data Sources

  • EMA SPC Suprefact (buserelin) EMA Summary of Product Characteristics

Related Tools

Medication Level Plotter

See blood level curves for this compound

Dose Calculator

Calculate reconstitution and draw volumes

Split Dose Calculator

Divide your weekly dose into multiple injections

Track Buserelin with Doseline

Reminders, medication level charts, injection site rotation, and protocol tracking — all free, all private.

Join the waitlist

Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.

Doseline provides informational tools only. It is not a medical device and does not provide medical advice. Always consult a qualified healthcare provider.